A Brief Note On The Major Micro Vascular Complication Of...

Background: Diabetic nephropathy is the major micro-vascular complication of type 2 diabetes mellitus (T2DM) and is the main cause for end-stage kidney disease. In view of metabolic derangements of T2DM, we went further to investigate the role played by oxidized low density lipoprotein (ox-LDL), toll like receptor 4 (TLR4), lipocalin-2 (LCN2), and omentin-1 in DN. Patients and methods: 15 normo-albuminuria T2DM, 15 micro-albuminuria T2DM and 15 macro-albuminuria T2DM in addition to 15 healthy volunteer who served as control group were enrolled in this study. Demographic and clinical data were recorded. Plasma Ox-LDL, omentin- 1 and urinary LCN2 levels by immunoassy and TLR4 mRNA level with real time PCR were assessed. Results: TLR4 gene expression, Plasma ox-LDL, urinary LCN2 levels were increased in T2DM cases as compared to their allied control group with the higher values were for macro-albuminuria T2DM cases. Meanwhile Plasma omentin-1 level was decreased in T2DM cases when compa red to their allied control group with least values were for macro-albuminuria T2DM cases. Also there were positive correlations between TLR4 mRNA, ox-LDL, urinary LCN2 levels and serum creatinine, fasting blood glucose, urinary albumin/creatinine ratio, meanwhile omentin 1 showed negative correlations with serum creatinine, fasting blood glucose, urinary albumin/creatinine ratio. Conclusions: Ox-LDL, TLR4, LCN2 and omentin 1 may confer a relevant role in diabetic nephropathy development andShow MoreRelatedMedical Test with Answers Essay example16933 Words   |  68 Pagesshould the nurse administer? A. 0.5 ml. B. 1 ml. C. 1.5 ml. Correct D. 2 ml. To correctly tabulate this problem, use the formula: Desired/On Hand, Or the algebraic formula: 75: x = 50 : 1. 50x = 75 x = 75/50 or reduced to 1.5 ml (C). Category: Fundamentals  ¶ The nurse is preparing to administer IV fluid to a client with a strict fluid restriction. IV tubing with which feature is most important for the nurse to select? A. Micro drop factor. B. Drop factor of 15 gtt/ml. C. An intact inline filter. DRead MoreComprehensive 1 Essay18452 Words   |  74 Pagesantiviral agents (D) are ineffective. Symptoms, such as fever, chills, headache, stiff neck, fatigue, and swollen lymph nodes are more typical, not nausea and vomiting (C).   Category:   Community Health Awarded 1.0 points out of 1.0 possible points. 2. 2.ID: 310982379 The nurse is planning a wellness program aimed at primary prevention in the community. Which action should the nurse implement? A.   Immunizations that decrease occurrences of many contagious diseases.  Correct B.   Blood pressure screenings

The Organizational Structure Of Apple Incorporation

The Organizational Structure of Apple Incorporation Name: Institution: Course Title: Date: The Organizational Structure of Apple Incorporation Apple Incorporation is a multinational company that deals with technological products and is found in the United States. The company creates communication devices, consumer products, and entertainment products for example iPad, iPhone, and iPod. Apple Incorporation was launched in 1976 and has its headquarters in Cupertino, California. Steve Jobs, Ronald Wayne, and Steve Wozniak were the founders of the company (DuBrin, 2012). Apple Incorporation is the second largest company in the world that deals with information technology. It operates in more than fifteen countries and has multiple retail stores that rely on an estimate of 72,800 employees who are employed in a full-time capacity. The employees of Apple Incorporation follow the assigned organizational behavior where they operate without any supervision (Lashinsky, 2012). The work environment integrates negligible rules and regulations in order to promote innovation among its members. The employees have a two-way communication strategy with the management and directors of the company. This ensures that the needs and concerns of the customers are evaluated to ensure they are satisfied. Job description and role of the employees are important factors that impact the communication process. The demands for secrecy in the company make the communication process difficult thatShow MoreRelatedThe Social Performance Of Apple Incorporation And The Impact Of Corporate Social Responsibility On The Multinational Business Organization987 Words   |  4 Pagesthe social performance of Apple incorporation and the impact of corporate social responsibility on the multinational business organization. a) The nature, structure and types of products and services provided by Apple Since its inception in the late 1970s, Apple incorporation has brought a tremendous revolution in the field of technology. The multinational firm has received a worldwide acclaim as a consumer electronics provider. Apple incorporation design, develop and sell consumerRead MoreApple s Phone Service : Apple Inc. Essay3113 Words   |  13 Pages Apple s Phone Service APPLE COMPUTER COMPANY INTRODUCTION Apple Incorporation is an American computer company that is headquartered in Cupertino, California. The company is concerned with designing, developing, marketing and selling computer software, consumer electronics, personal computers and online services. The company is known for the production Mac computers, iPhone smartphones, iPod media players, Apple Watch smartwatch and iPad tablet computer. Apple incorporation is also concerned withRead MoreLeadership: an Integrative Approach1334 Words   |  6 Pagesleaders that have been credited for or blamed for inspiring people to provoke important historical events. The process of shared influence Yukl (2010) describes, may be as fascinating as recognizing the strength and uniqueness of Apple’s organizational culture and understanding that such knowledge and ability to inspire others was inside Steve Jobs’ powerful mind, and intriguing as accepting that there are scorned personalities that their subordinates conspire to murder them which is the caseRead MoreEssay on Assignment 1 Social Performance1380 Words   |  6 Pagesnature, structure, and types of products or services of Apple, and identify two (2) key factors in the organization’s external environment that can affect its success. Provide explanation to support the rationale. Apple Inc. is a well-known computer manufacturer, smartphone and digital devices device maker. 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It seems that the ideologies in Apple’s organizational cultureRead MoreThe Merger And Acquisition Of The Quaker Oats Company1202 Words   |  5 PagesGatorade and sought to expand their beverage line with the merger/acquisition of Snapple Beverage Company (SBC) (History, 2011). SBC was founded by Leonard March, Hyman Golden and Arnold Greenburg in 1972 (History, 2011). SBC made an all-natural apple sodas, seltzer water, and later tea (History, 2011). It wasn’t until 1994, when sales along with distribution, that QOC was able to purchase the Snapple product line of beverages (History, 2011). QOC purchased Snapple at a whopping $1.7 billion U.SRead MoreApple Inc.2382 Words   |  10 PagesApple: An Introduction Apple Incorporation is one of the largest organizations dealing into Information Technology. Apple has a host of products ranging from Laptops, Desktops, Mobile Phones and Multimedia Devices. 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Business Model4927 Words   |  20 PagesContents How apple was formed 2 Apple?s Business overview 2 Apple?s business model 3 The ideation phase 6 APPLE?S ORGANIZATIONAL STRUCTURE. 7 Feature of Apple?s organizational Structure. 8 Advantages of Apple?s organizational structure 9 Disadvantages 9 Apple?s organizational chart 10 Apple?s philosophy of innovation 11 Innovations implemented by Apple?s ownership/management team 14 Methods and strategies used to create sustainable competitive advantage 18 Methods and strategies that Apple used to createRead MoreApple Incorporateds Financial Strategy: An Analysis2411 Words   |  10 PagesIntroduction Apple Inc is a multinational company specializing in designing, producing and marketing of Apple computer, iPod, iPhone, iPad, and Mac, and other mobile communication devices. Apple also designs and market professional software application such as Mac operating system, iOS, iCloud, and other range of accessories. The company sells its products globally through varieties of channels such as retail stores, online stores, third party wholesalers, direct sales and resellers. Bulk of Apple customersRead MoreApples Ethical Practices3897 Words   |  16 Pagespersonal ethics to match those of the organizations ethical culture. For this reason, business ethics theory indicates that an organizations ethics are evident in its organizational mission and vision (Hummels Timmer, 2004). This is because the mission and vision determine organizational structure and culture, and thereby organizational and individual behavior. In addition, an organization is driven to establish social responsibilities through their social standards and practices. They develop social

My Move from Bangladesh to America Essay Example For Students

My Move from Bangladesh to America Essay Sometimes, something happens in our life that changes our whole perspective on living. Most of us have experienced such an event. When I reflect back to my past, the most significant event is coming to this country. On June 19, 2012 I came to this country. I was inundated with dreams but after arriving here, all of my expectations were shattered in a moment. Nothing was what I had expected. The problems appeared like high dark mountains in front of me and my family. But one thing that kept my broken spirit alive was the quote from Benjamin Disraeli, Circumstances are beyond the control of men; but his conduct is in his own power. The first problem I faced here was the language barrier. I came to this country with very little knowledge of English. I couldnt understand what others were saying to me and neither could my family. With this poor knowledge of the English language, my family and I struggled to communicate with other people and were lagging behind. I took learning the English language as my challenge. My enthusiasm to learn English forced me to take extra classes in my school until 6 oclock. I read many articles in newspapers and watched many movies to improve my English. My teachers also helped me very much. With my strong determination, now I can speak and write English quite better than before. Even though I am not an expert, I am satisfied with my progress. At first my grades were lower than I was accustomed. But now I have improved my grades and got many awards for my educational achievement including â€Å"Arista. The next barrier was the economy. Here in the United States life is so hard and now-a-days jobs are becoming scarce. As my parents werent good in English, they were unable to get good jobs. I found it my responsibility as the eldest son to help support my parents. As I had after school classes, I was unable to get a part time job. However, this summer, I managed to get a job. I started to earn an income for the first time in my life. I gave all of my money to my parents. I also taught my parents English. Now their English has gotten better than before! I have a younger brother who fell in an ocean of problems. After coming here, he didnt understand even a single word in school and there was no one to look after him when my mom was at work. After coming back from school, I helped him to finish his homework and did all of the things he needed after doing my own homework. It was a joy to see my brother doing excellent in his school. As a brother and also as his tutor, I felt proud of him and of myself. America has taught me the definition of life. In Bangladesh I went to school, came home and hung out with my friends. My dinner was ready, my room was clean, and I didn’t need to care about my younger brother or anyone else. But now, I have to join forces with my parents to survive in this extreme situation. I have to accept whatever comes and fight with my own arsenals to keep myself from capsizing. Darwins theory of evolution may be applicable for me- survival of the fittest. If I can fight against this harsh situation, I can survive. I am satisfied with this extreme situation. These road-blocks have given me the opportunity to learn about myself and instilled confidence in me. With hard work, determination, and responsibility, I am capable of accomplishing anything that comes before me. This situation is preparing me well for my future, when I will be the head of a household or perhaps my own business